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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea833721ba0839f3ce79c0c0450a9a506a35027674f2c62a3ca77cfc04af182c' 
  AND token = 'zNd590/9YuCSeE3b+ewWmpagSJJ4VNSldcjqSCYoOlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}