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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3917a4a7f673bd5218d19b9388d2c6f40a2e5b874c304e967061f15a1f5c42f7' 
  AND token = 'ub70ur55x0w9NJeiWysw4i1TcPylvLoCfNi953qqyis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}