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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a92bc05120d2184493171bf067e45f89aebab56e35edfa2b489a531693f413' 
  AND token = 'Z73GsuUMgK/ui5dusTbWGl6BTC5z8gzWXNtkQTGkUns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}