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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be745ffedd20a24ec5997a6b73192a12b3c590fa0b915bc33c27c0e9bc67ddfd' 
  AND token = 'T+7wGVRbtKl2rhRvV+CyzEVZYxYdKEZl/Evlj0E3bro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}