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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6586b9ab3c9d878268bb91adbf0c6b628b6bafafbd81ee6b53f6b2203838cbf9' 
  AND token = '4a/zOL1jxGLUn8BCVnL12I72gqOI/+xGB65R0ES2zBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}