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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dd421c7794a57bed3012ddf66a36235dfa1a4fde2c9d52253b7c5fe7093e88' 
  AND token = 'wskOf/6VCHjqHeFhcgDHwLaNvwyj6+bQx6mLtdPJ3cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}