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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f14a1de204beb0cbd2fa23813cce144daeb881322f1a81c9c22d7c5cc5f7ce3' 
  AND token = 'HtYlRkd3Lo0Hd5RI/L6x/46FNAR6YaYffipTmuFaUZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}