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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffe03c407630a1370060003b74a8259c4d7b0ea4ed02de9ad1ed6131c50a64a' 
  AND token = 'aCVEHui/uz9dLxaiAyoxR6+pEW2AA1z8Vp1TpsHY8FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}