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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d4ddabb24429e0715ba50b517f1ffd1ba02eefb964ccd74a6eea68194ab145' 
  AND token = 'mRjeCqy077NRB6Gw9IPbYS63gl9Vnb6LiBO8nPqLRCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}