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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d58289b59415a74144a435e53a9984ef5931bb8d70aee076f2ec8dc03fdeab' 
  AND token = '3D/lziTNw3fNN2Zag2a+kDIiqHBkU071oPxkA1FoTHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}