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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52ab907da834ebe3bae3ee1a8e82665c4ab7da5b2b3f9c7e2ac378196d33da5' 
  AND token = 'freGR0eu7mFIJxla0FyuDRf1OVfcVRHQpbhvzxLbFXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}