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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44acd7a0699a43e01d34d57320d07455422b3eaf5698af7f38c037b729447ddc' 
  AND token = 'SvESFf/4zj4PE1MDyxh7UmGMDCbBbydYd0qBNnhHP70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}