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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4245a0ef6a319d0b9adbf59296a58485c23af7b26ef517608fd0fd8653e3fcec' 
  AND token = 'ZMkGOxl+trUR93gSEMxX9aQk4LC72LKWo0PMo45va88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}