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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df543e2cf6a030f88d4fd8e7ce9e243f2fa299e8c67b657781897ea2bfe9de0c' 
  AND token = '5tlKQ0fmd5b5jzMRz73nYeJRlg7xkHJhSuvrXQgSOKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}