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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e0f6cc7fa7dc38870a25bbd116c220f4536a55e6beaba330bb129fc24e29d4' 
  AND token = '5MfMnXXKQb7iiMvro0X1niadFkeJEVOz2WIUNVi8G58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}