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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efef19dbaedf8ababd28233cb65a2d44d178a0e892a9faf41674a703c11721ff' 
  AND token = 'G3Cotao69teaup/XGGw3IPjYHARw1TVKzkCHaBW8UPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}