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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87543675f1e5ac5bea0524a40569ee8763cd9bcf8009772ac8912b89e86229db' 
  AND token = 'DNa3/rWhUv77pwwrWlIwlfVuYVdMr0VnmW6XMqXHOcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}