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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a395b2b9817e834b15de4e816b9f88f75dfc72681c2256e4288b4ebb666ae0ee' 
  AND token = '/o4OTec9WhDtLysTxhQEnmOIgUUk4ObiypV8Go/tzUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}