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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4331f534957720416b62a10093cc9a3bc30d4212a59caf6738db0df730247ed4' 
  AND token = '+wG3U15zUdnbx0rvO9CmCuLVJUTkaFlnbNB0HlLWjaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}