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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe1ca70ed370f062c57b65017cd974afd1755d78bff1f223d195a3ca207406d' 
  AND token = 'amRyrbaVFCTj++K0008r83hjE2GCCapxJNH9KD+T6OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}