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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac8c31be877fb9879b8cccfa83093c53b221cd52151f0b5c36891665de89cf8' 
  AND token = 'OeR5/Zc8ZMGKezdbpNAzF7Befk7xreuV1zYu485AceI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}