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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef808a823305ced609af82ef508ab4c89bb93971a44916e594d52e7368582a3b' 
  AND token = 'NkCg6duzQ4tEwqwAlcU7YMQqwtGRmJDSINZ40CBp9kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}