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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb66ad196061e2d2525ae5881ad9e65de065ec3271f0202e22b2763bcc90aa01' 
  AND token = 'kcfJg1+ItVArYYa8rwHb/R0Qs61tAezq6jL03cVA5ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}