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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c2bda3b31d5a48d0ae903cd29ce3105d50ed06a2e099a32e83de559d1770a5' 
  AND token = 'yoSjB1h2IKBnNZ1y9TocCm/NupaA9g21XNreWFRNS54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}