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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f23e0dee15d72d5106c948ebc59d3616f5622bdfb82b48cef90133577acca2' 
  AND token = 'XMJWbRfaksSiIyvUzK5IcdSqjqzXkpYy+2RfwyE4HGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}