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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49718fc7054d8387293855e28734049576d6281336da6fe503f0a4258c83e2d2' 
  AND token = '0K22/tsmg6Nh/sK9POnusjSq3FKGH7xC78FNX2CGQbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}