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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d3bd0c4c9053f5dba3c1dda0586261a6836f7bfbfa46ce2adb842543c01478' 
  AND token = '/FXro1N5w1ztF/8sMbKoCtCFKZHIaFXHKekPR7GW+us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}