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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4226bc06ad4508baa881ca96699a3f646a1804cc985cc40d0cd15742a4ffb2df' 
  AND token = 'VAu+WZMNkE+IA3B7kWuDlsF9RrRwCfRMR236BX6Uqqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}