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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f6773ff2def42e7cc04727c55acbbfa729bf9ca158f4cbc4906f6b80aa7c5c' 
  AND token = 'jP6qzVWQG5y2cZ3vIOjQSz7GST8LwhAHkx2dZpKYykk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}