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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735f1b1a08190cc94a48430c29d9fd7d3c507c22e8bbfcaef45d5fafc2410980' 
  AND token = 'odjyHnSWTB2d7VPl7ZfrEot/pcHsmgp9XFnpXzJ9y2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}