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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28580a361c58720d8ec71f305b2f8d95557ce586b87567766e6755e1da068171' 
  AND token = 'wz3UW3TDExhqpoB6lm4CSRfyxhUMoHFBl1Lw2SqzM9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}