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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce947ce8574a6a09fb2260c8b8107c4b299b0ee1bd2afae5b7d4a40a46010ce' 
  AND token = 'IkAHJA9jmIsNUCb6PIP+YCAI2f36tG6iBYxeJMqXQkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}