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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efef4970a98efade4606e4c6a33e68b7ee9fec71fe29c321a77ca606dc3b4b0' 
  AND token = 'sE/41yUDwcBduLeJsbDlePTJb33EAJSasYY1JrdVNjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}