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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52967aa10b47a8987364b48294f67b15d776244239c1a4a03388dcd124d0727' 
  AND token = 'zFdf9+X1Ox1kIQiHPGn3XCmLqMmEQWPyTRP9mSRgV6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}