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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f616bd5ec7ca148f3f44f6e6303d8a714b7f70fb85f31ea7c0a551f03792930a' 
  AND token = '2dJaDhdg7j4YPsJ0DlT1YKeQclFOI/wF8sm1w4naiiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}