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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455351d4903962850d48314947f3756277005e20ab8f80d0b2b7e031185c34f0' 
  AND token = 'j77WTeHaqnY44TcCPTMuDJ3Suc1+AomwtyAX+aCl7WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}