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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2be352ebef5069e5b059e0ad5bcb75cb9d72434af2a12b679ef9bb88cec3cd' 
  AND token = 'GUVsII5JF7u0JQ+M8D9hNlBineYn71rXTR23Sx/b+Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}