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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0b6ba600f07ef4988fa9637b2dae439de8dc7e7ee8f3ce2ba4209d05c08614' 
  AND token = 'ys7/E55bLSTTFAvGRfqioSTKYaAq4JuJU9dzEBAXoGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}