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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7021503f7d1cdb191c2f3ca405511875512ff3e3607910cd7b89f0509bd03600' 
  AND token = 'Ic8oc5A4h30OwkZHH3HLBbFd5X4EdAKpysNkCX41aN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}