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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e1d21802b4f0e2faa209e050cf0646fee3b13079241d9d8c54bd46c3c6e246' 
  AND token = 'TXjVtsQb+xrO/VIBOm/3ddWa/k9pxJXFO5GPXX6rIko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}