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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dfc1fe9bd8db8213a7a383ca85db3c8b2c6a1de8493cefc3c70e324a970372' 
  AND token = '8IafWacN8Cv2BmmaxkE3GTZe0LMhPvCX7ZoBtEDcGIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}