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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628218f1813c001e2c09dabfeccfebb2434ff58c417e1f6f48931e0ca2a959a0' 
  AND token = 'OJ/IZOGQiGStyzaUi4HPUqVAN9x3a9cxMxx+mWDrfKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}