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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1277a169dca0d19a09ab1daee784f2a1b9c5089aea1db645097dd94e5f61b09b' 
  AND token = 'iQGMP0LGmrMtGdRXuArJnEX+sLQ9x5f57lUbnuOF3To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}