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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc49ad9363c278d99f81c3616570ac79f22ef5eeb28cdd697d1ae8078bed5d4' 
  AND token = 'cJntd0h1l6RtXnvK3K9jKnGaurDb74ijARwZ+TUd+aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}