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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa6002feb911a9a6176e779c13e134fab4abebce9f7ecd3000ef2497442fcfd7' 
  AND token = 'Q5Pntlv/SgtMuU00IncEfokEVbM45uBdSQAftgZdyvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}