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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327c7859343ad5d574bcef8d50d0a5441ea186cf14e72df0576ca9a3442190f8' 
  AND token = 'NVp0MaqyiEswuSjSjiVdTxQQRZNx6vh4lNpXU8ej0rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}