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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e8d77c511b83c02f89ad3bb8dd63dda8855b009b699bce0b8ee024aaaf3e58' 
  AND token = 'ZbNYLZiLI1HDGh3+SnZJLrWz1lu1j+lgnPepE2m9ukk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}