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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18e52fdc83131b270086e0063878736d71bc00ab5d0ffcbab508002e98af368' 
  AND token = 'VrVqm6iCt/XQ9vjAzofwZvms4ItjNAEhS0TmANYS55k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}