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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc21f711f3b2e0ba3348fbe9c2076a61d0637ac2ee59cff486ba2403849789ac' 
  AND token = 'yK0ZpWZe9I38QZ3/1kCYAITT36CDTCmk13fGrsL8Oy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}