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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b529ba5c3553c3a0420e002b5c277056638cd9067fee7df7dea404990fffb7' 
  AND token = 'QCtBXR+kJZiCpoe/5YyCy6gu2VrgZ9EN0w0AgY8N9gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}